Creating a New Kind of Doctor
We recruit and train physician leaders as comfortable taking on systemic challenges in health as caring for individual patients.
Discovery to Impact — Faster
We reward creative thinking and encourage rapid experimentation, using collaborative programs to speed promising research to market.
Improving Care. Improving Health.
We’re here to make health — including health care — better. The end goal is a complete revolution in how people get and stay healthy.
In This Section
More Information
Health in the Landscape of Life
Enabling the healthscape, the ecosystem outside the clinic, requires improving the system to pay for health drivers.
More Information
Meet Dell Med
We’re rethinking the role of academic medicine in improving health — and doing so with a unique focus on our community.
More Information
Make an Appointment Give Faculty Students Alumni Directory

William Matsui, M.D.

UT Health Austin Care Team Member

University of California, San Francisco School of Medicine

AB Biochemistry
Harvard College


Residency, Internal Medicine
University of Washington

Fellowship, Medical Oncology
Johns Hopkins University School of Medicine


William Matsui, M.D., is the vice dean of research at Dell Medical School. He is also a professor of oncology and internal medicine. He specializes in caring for patients with cancers that involve the blood and bone marrow as well as bone marrow transplantation.

Matsui came to Austin from the Johns Hopkins University School of Medicine, where he was a professor of oncology and served as the director of the Multiple Myeloma Program and the co-director of the Division of Hematologic Malignancies. Matsui received his undergraduate degree in biochemistry from Harvard College and his medical degree from the University of California at San Francisco. He completed his residency training in internal medicine at the University of Washington in Seattle and his clinical training in medical oncology at Johns Hopkins.

Matsui has carried out laboratory-based translational research throughout his career and focused on studying cancer stem cells, tumor cells with enhanced growth potential and their role in clinical oncology. His laboratory first identified cancer stem cells in the plasma cell malignancy multiple myeloma in 2003 and subsequently in other cancers including lymphomas, leukemias and pancreas cancer.

Matsui’s laboratory has also demonstrated that several pathways regulating normal stem cells, including those involved in embryonic development, are abnormally activated in cancer stem cells. Importantly, the Matsui lab has emphasized translational research and successfully built on their laboratory findings to carry out clinical trials testing novel therapies.

Professional Affiliations
  • American Society of Hematology
  • American Association of Cancer Research
  • American Society of Clinical Oncology
  • American Society for Blood and Marrow Transplantation
  • The American Society for Clinical Investigation
Awards & Honors
  • Scholar in Clinical Research
    The Leukemia and Lymphoma Society, 2009-2014
  • Kimmel Foundation Scholar
    Sidney Kimmel Foundation for Cancer Research, 2007-2009
  • Teaching Award, Department of Oncology
    Johns Hopkins University School of Medicine, 2006
  • Teaching Award, Department of Medicine
    Johns Hopkins University School of Medicine, 2004
  • The George Santos Award
    Leukemia and Lymphoma Society, 2001