Karen Keough earned her Bachelor of Science degree in psychology at the College of William & Mary where she was inducted into Phi Beta Kappa and Omicron Delta Kappa honor societies. She also studied molecular biology at Hood College. She earned her medical degree from Johns Hopkins University School of Medicine where she was nominated to the Alpha Omega Alpha honor society. She completed her pediatrics residency at Wilford Hall United States Air Force Medical Center, where she also served as chief of residents.
Following her residency, Keough pursued a fellowship in pediatric neurology at Duke University. After three years in the Air Force as a child neurologist, she completed an additional fellowship in clinical neurophysiology and epilepsy at Baylor University School of Medicine. She then returned to Wilford Hall Medical Center to serve as director of epilepsy services and chief of child neurology. She maintains board certification in pediatrics, neurology with special qualification in child neurology and epilepsy.
Keough initiated the Child Neurology Residency program at Dell Medical School at the University of Texas and serves as its program director. Additionally, she holds the position of chair of the Child Neurology Society Educational Special Interest Group and serves on the Neurology Child Examination Committee for the American Board of Psychiatry and Neurology.
Keough founded and functions as co-director of the Comprehensive Tuberous Sclerosis Clinic in Austin. Her primary clinical focus is refractory epilepsy, though she continues to participate actively in the general child neurology hospital service to work with trainees and maintain her edge for treating other clinical neurologic conditions.
Keough has lived and worked in Austin since 2006.